課題組簡介
俄亥俄州立大學(The Ohio State University)醫學院(College of Medicine)鄭慶飛課題組致力于腫瘤代謝和癌癥表觀遺傳學的基礎和轉化研究。課題組將綜合應用化學生物學和合成生物學等手段研究飲食、代謝和微生物組對于腫瘤微環境的影響并基于此開發新型的癌癥免疫療法。
課題組長鄭慶飛博士2012年畢業于清華大學化學生物學基礎科學班,期間入選首屆清華學堂人才培養計劃。于2017年在中國科學院上海有機化學研究所獲得博士學位。2017年7月到2021年7月在紀念斯隆凱特琳癌癥中心(Memorial Sloan Kettering Cancer Center)從事博士后研究工作。2021年8月加入俄亥俄州立大學醫學院放射腫瘤學系(Department of Radiation Oncology)和癌癥代謝中心(Cancer for Cancer Metabolism)任助理教授(Assistant Professor)。此前的研究領域包括:微生物代謝產物生物合成途徑的遺傳基礎和酶學機制、分子改造以及相關藥用機制的研究;活性代謝產物對于腫瘤細胞表觀遺傳學調控通路的影響;基于表觀遺傳組改造的合成生物學。已發表研究論文四十余篇(其中已通訊作者和第一作者發表文章三十余篇),曾榮獲2017年吳瑞獎、研究生國家獎學金等多個獎項,并獲得2020年布拉瓦尼克區域青年科學家獎(Blavatnik Regional Awards for Young Scientists)提名。
招聘崗位及條件
1、招聘崗位:博士后(3名)
2、招聘要求:
1)化學、生物學、藥學和醫學等相關專業博士畢業,在相關領域的重要學術期刊上有研究性論文發表;
2)對科研有熱情,有優秀的英文聽說讀寫能力;
3)優先考慮具有有機化學(全合成)、多肽合成、化學探針開發、酶學機制研究、結構生物學、蛋白質/代謝組學、厭氧微生物操作和生物信息學經驗的申請人。
薪酬待遇和環境
根據個人科研工作能力、經驗和美國NIH博士后薪資標準發放。課題組將提供世界一流的研究平臺和合作環境,并根據興趣與需求最大程度地支持個人的職業發展。
俄亥俄州立大學坐落于美國俄亥俄州首府哥倫布市(Columbus),是世界著名的研究型大學(2021年U.S. News世界大學排名45),也是美國最頂尖的公立大學之一,被譽為公立常春藤(Public Ivy)。大學主校區占地面積65平方千米,是全美面積最大的校園之一。俄亥俄州立大學醫學院也是美國著名的醫學院之一(長期位居全美排名前30),其中的詹姆斯癌癥醫院和索洛夫研究所(The James Cancer Hospital and Solove Research Institute)是美國規模最大和最先進的癌癥研究機構之一。哥倫布市是美國人口增長最快的城市之一,基礎建設優秀,充滿活力,生活成本低。在Numbeo公布的2016年全球最宜居城市排行榜中哥倫布位列全美第2,北美第3。
應聘方式
請將以下材料以PDF形式發送至ZhengLab.OSU@gmail.com,對于符合要求并通過初審者,將會通知安排面試。招聘啟事在崗位招滿前有效。
1、個人簡歷;
2、3位同行專家的推薦信或聯系方式;
3、研究興趣和個人計劃陳述。
Three postdoctoral fellow positions are immediately available in Dr. Qingfei Zheng’s laboratory in the Department of Radiation Oncology and Center for Cancer Metabolism at The Ohio State University. The positions are supported by the Ohio State University Comprehensive Cancer Center (OSUCCC) to study the interplay between metabolic syndrome and cancer development. The Zheng Lab aims to apply chemical and synthetic biology approaches towards studying cancer metabolism, epigenetics, and tumor microbiome for the development of new personalized cancer therapies. The long-term goal of the lab is 1) to understand the mechanisms of cancer-related metabolic disorders and epigenetic dysregulation and 2) to develop new cancer therapeutics at the “atomic” level. The Zheng lab will focus on both basic and translational research areas. The laboratory collaborates with outstanding faculty in the newly established Center for Cancer Metabolism and Pelotonia Institute for Immuno-Oncology. There is a highly interactive and collaborative environment within OSUCCC. Postdocs will get great training opportunities and closely interact with the world-class outstanding faculty members.
A young lab cannot take off without motivated people. Chemists and biologists from any fields are welcome to join the Zheng Lab. Successful candidates are expected to work closely with Dr. Zheng in the lab to design and carry out experiments, analyze, organize, and present data in written form and to meetings, and to write papers and grants. Salaries, stipend, and benefits are highly competitive and commensurate with university policy and NIH guidelines.
Postdoctoral fellow candidates should hold a Ph.D. degree (or will complete one soon) in chemical or biological science areas. Prior experiences with molecular biology, biochemistry, peptide synthesis, enzymology, proteomics/metabolomics, bioinformatics, and anaerobic microorganisms are a plus but not required.
Interested candidates should send a cover letter summarizing their research interests and CV with a publication list and names and contact information of three references (preferably in a single PDF) to “ZhengLab.OSU@gmail.com”. Informal inquiries are also welcome.